Family name Santana Yepez (Santana Yepez 
) , in all the world, is a very rare last name. The family name Santana Yepez is habitual in Latin America and the Caribbean, particularly Ecuador, where it is a rare surname, and Chile, where it is a very rare surname.
| VARIANT | COUNTRY |
|---|---|
| Santana Yepez | Chile, Ecuador |
Niko, Luz Camila, and Felix Isaac